Scientist/Senior Scientist, Analytical Sciences, CareerBuilder, Gaithersburg, MD
CareerBuilder -
Gaithersburg, MD,
US
Scientist/Senior Scientist, Analytical Sciences
Date Posted: 2024-04-24
Job description
Do you have a passion for science? Would you like to apply your expertise to impact a company that follows the science and turns ideas into life changing medicines? Then AstraZeneca might be the one for you!
At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then youre our kind of person.
About AstraZeneca in Gaithersburg, MD:
Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most innovative technology and lab spaces, all designed to inspire collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration.
The Gaithersburg site offers a variety of amenities to help boost productivity and help keep our employees happy and balanced. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center. This is where youll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams.
Summary of the group:
In Analytical Sciences in Gaithersburg, MD youll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients lives. Were constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for discovery and a pipeline to show for it. Were pioneering innovative research and exploring novel pathways across key therapeutic areas including oncology, respiratory, inflammation and autoimmunity, cardiovascular and metabolic disease, and infection and vaccines. And were industry-leading in immunology, protein engineering and translational science. We offer a unique and strong collaborative network as part of the AstraZeneca family, as together we explore synergies between small and large molecules.
Main Duties & Responsibilities:
In this role, the Scientist/Senior Scientist will develop and supervise method development and testing in support of product characterization, CQA assessment, and process development. They will be responsible for providing high quality data to support the characterization of biopharmaceuticals and aid in drafting of CMC documents for regulatory submissions. For the senior scientist position, there will be additional emphasis on developing product characterization methods, informing our development strategy, and mentoring junior scientists.
Support protein therapeutics characterization using various biochemical and biophysical techniques, especially mass spectrometry-based methods (for example, peptide mapping for PTM quantitation, disulfide bond mapping, and intact mass analysis).
Maintain laboratory instrumentation and coordinate and supervise user training and instrument service
Support pre- and post-IND regulatory submission by authoring and review of analytical sections
Supervise and mentor junior scientists
Education & Experience Requirements:
Scientist: Bachelors degree with 5+ years or Masters degree with 2+ years
Senior Scientist: Bachelors degree with 10+ years or Masters degree with 8+ years or PhD with 0+ years of related experience in industry or academia.
Required Skills:
In-depth knowledge in biochemical and biophysical characterization of proteins
Experience with mass spectrometry (LC-MS/MS, peptide mapping, disulfide bond mapping, intact mass analysis)
Experience with one or more of the following analytical techniques: liquid chromatography (SEC, IEC), capillary electrophoresis (CGE, CE-SDS), capillary isoelectric focusing (cIEF)
Ability to work in a highly matrixed structure and to interface and share ownership of projects with different groups within research and development
Desired Skills:
Experience with large molecule development in the pharmaceutical or biotech industry
Experience with authoring of CMC documents for regulatory submissions
Experience operating and developing automated sample preparation or analysis methods
Experience in developing internal tools and machine learning in R/Python
Experience with computational structural biology techniques such as structure prediction, docking, and molecular dynamics
Why AstraZeneca?
At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognising their potential. Join us on our journey of building a new kind of organisation to reset expectations of what a bio-pharmaceutical company can be. This means were opening new ways to work, pioneering groundbreaking methods and bringing unexpected teams together. Interested? Come and join our journey.
When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform to connect, work at pace and challenge perceptions. Thats why we work, on average, a minimum of three days per week from the office. But that doesnt mean were not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world
.
So, whats next!
Are you ready to bring new ideas and fresh thinking to the table? Brilliant! We have one seat available and we hope its yours.
Where can I find out more?
Our Social Media, Follow AstraZeneca on LinkedIn
Follow AstraZeneca on Facebook
Follow AstraZeneca on Instagram
#J-18808-Ljbffr
At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then youre our kind of person.
About AstraZeneca in Gaithersburg, MD:
Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most innovative technology and lab spaces, all designed to inspire collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration.
The Gaithersburg site offers a variety of amenities to help boost productivity and help keep our employees happy and balanced. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center. This is where youll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams.
Summary of the group:
In Analytical Sciences in Gaithersburg, MD youll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients lives. Were constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for discovery and a pipeline to show for it. Were pioneering innovative research and exploring novel pathways across key therapeutic areas including oncology, respiratory, inflammation and autoimmunity, cardiovascular and metabolic disease, and infection and vaccines. And were industry-leading in immunology, protein engineering and translational science. We offer a unique and strong collaborative network as part of the AstraZeneca family, as together we explore synergies between small and large molecules.
Main Duties & Responsibilities:
In this role, the Scientist/Senior Scientist will develop and supervise method development and testing in support of product characterization, CQA assessment, and process development. They will be responsible for providing high quality data to support the characterization of biopharmaceuticals and aid in drafting of CMC documents for regulatory submissions. For the senior scientist position, there will be additional emphasis on developing product characterization methods, informing our development strategy, and mentoring junior scientists.
Support protein therapeutics characterization using various biochemical and biophysical techniques, especially mass spectrometry-based methods (for example, peptide mapping for PTM quantitation, disulfide bond mapping, and intact mass analysis).
Maintain laboratory instrumentation and coordinate and supervise user training and instrument service
Support pre- and post-IND regulatory submission by authoring and review of analytical sections
Supervise and mentor junior scientists
Education & Experience Requirements:
Scientist: Bachelors degree with 5+ years or Masters degree with 2+ years
Senior Scientist: Bachelors degree with 10+ years or Masters degree with 8+ years or PhD with 0+ years of related experience in industry or academia.
Required Skills:
In-depth knowledge in biochemical and biophysical characterization of proteins
Experience with mass spectrometry (LC-MS/MS, peptide mapping, disulfide bond mapping, intact mass analysis)
Experience with one or more of the following analytical techniques: liquid chromatography (SEC, IEC), capillary electrophoresis (CGE, CE-SDS), capillary isoelectric focusing (cIEF)
Ability to work in a highly matrixed structure and to interface and share ownership of projects with different groups within research and development
Desired Skills:
Experience with large molecule development in the pharmaceutical or biotech industry
Experience with authoring of CMC documents for regulatory submissions
Experience operating and developing automated sample preparation or analysis methods
Experience in developing internal tools and machine learning in R/Python
Experience with computational structural biology techniques such as structure prediction, docking, and molecular dynamics
Why AstraZeneca?
At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognising their potential. Join us on our journey of building a new kind of organisation to reset expectations of what a bio-pharmaceutical company can be. This means were opening new ways to work, pioneering groundbreaking methods and bringing unexpected teams together. Interested? Come and join our journey.
When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform to connect, work at pace and challenge perceptions. Thats why we work, on average, a minimum of three days per week from the office. But that doesnt mean were not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world
.
So, whats next!
Are you ready to bring new ideas and fresh thinking to the table? Brilliant! We have one seat available and we hope its yours.
Where can I find out more?
Our Social Media, Follow AstraZeneca on LinkedIn
Follow AstraZeneca on Facebook
Follow AstraZeneca on Instagram
#J-18808-Ljbffr